Philip had been steadily losing his grip—literally—for four years, since he first began to notice that his left hand would shake when he tried to hold his fork. He got really alarmed when his left foot started to go. Before long one could trace his route by the marks his toe left on floors after he went by. He bumped into doors, took a few spills, dropped things and began to lose the self-confidence that had given him the courage to start his own real-estate business. He also became steadily more fatigued and he mysteriously lost 20 pounds in weight. He was only 38 years old. Where would it end?